Erin Lindsey writes Venus Envy, which is about Zoe, a teenaged [at least when the series starts] transgirl and her awkward, hilarious life. The strip moves quickly in snapshot vignettes, mostly lighthearted and downright silly, but occasionally very heartfelt. I’m not so keen on the art [well, I’m just at the beginning of the archive], but I do enjoy the sympathetic characters and continuous slapstick. It’s a very playful comic. Read it ’cause it’s funny!
EDIT: The art improves vastly.